Description
SS-31 10mg – Mitochondria-Targeted Tetrapeptide for Cellular Bioenergetics Research
SS-31 (also known as elamipretide or MTP-131) is a synthetic aromatic-cationic tetrapeptide designed to selectively target the inner mitochondrial membrane. Its sequence, D-Arg-Dmt-Lys-Phe-NH₂ (where Dmt is 2′,6′-dimethyltyrosine), allows it to concentrate rapidly in mitochondria and bind with high affinity to cardiolipin, a unique phospholipid essential for maintaining cristae architecture and the assembly of respiratory chain complexes.
In laboratory research, SS-31 is studied for its ability to stabilize cardiolipin under conditions of oxidative stress, support efficient electron transport, reduce reactive oxygen species generation, and help preserve ATP production. These properties make it a valuable tool for investigating mitochondrial dysfunction in models of cellular aging, metabolic stress, ischemia-reperfusion injury, and energy metabolism.
At Esoteric Research, SS-31 is supplied exclusively as a high-purity lyophilized (freeze-dried) powder. This formulation helps maintain stability during storage and transport. Researchers reconstitute the powder with bacteriostatic water or another appropriate sterile diluent prior to use in experimental protocols. Every batch is produced under strict quality controls and is accompanied by Certificates of Analysis verifying identity and purity.
Key Research Applications:
- Investigation of mitochondrial membrane integrity and cardiolipin interactions
- Studies of oxidative stress, ROS modulation, and cellular energy production
- Research into mitochondrial function under metabolic or hypoxic stress conditions
- Exploration of bioenergetic efficiency and respiratory chain performance in cell and tissue models
Important Note: For research use only. Not intended for human consumption, diagnostic purposes, or therapeutic applications. Always consult relevant guidelines and perform your own validation before use.